Publications

Only in the last 10 y​ears are listed.

2017

Smith A, Javed S, Barad A, Myhre V, Li WM, Reimer K, Massicotte HB, Tackaberry LE, Payne G, Egger KN, Lee CH. (2017) Anti-proliferative and immuno-modulatory activities of fungi from north-central British Columbia. Int J Med Mushroom 19(6):

Li WM, Chan CM, Miller AL, Lee CH. (2017) Live-imaging of miR-430 in the developing zebrafish embryo using a specific molecular beacon. J Biol Chem 292:3568-3580

Rensburg GV, Mackedenski S, Lee CH. (2017) Characterizing the coding region determinant-binding protein-microphthalmia-associated transcription factor mRNA interaction. PLOS ONE 12(2):e0171196.

2016

Mehmood K, Akhtar D, Mackedenski S, Wang C, Lee CH. (2016) Inhibition of GLI1 expression by targeting the CRD-BP-GLI1 mRNA interaction using specific oligonucleotide. Mol Pharmacol 89:606-617.

2015:

Chohan M, Mackedenski S, Li WM, Lee CH. (2015) Human apurinic/apyrimidinic endonuclease 1 (APE1) has 3’ RNA phosphatase and 3’ exoribonuclease activities. J Mol Biol 427:298-311.

Barnes M, Rensburg GV, Li WM, Mehmood K, Mackedenski S, Chan CM, King DT, Miller AL, Lee CH. (2015) Molecular insights into the CRD-BP-RNA interaction through site-directed mutagenesis in the heterogeneous nuclear ribonucleoprotein-K-homology domains.  J Biol Chem 290:625-639.

2014:

Lee CH. (2014) DNA repair meets the RNA world. Antioxid Redox Signal 20:618-620.

King DT, Barnes M, Thomsen D, Lee CH. (2014) Assessing specific oligonucleotides and small molecule antibiotics for ability to inhibit the CRD-BP-CD44 RNA interaction. PLoS ONE 9:e91585.

Kim W-C, Ma C, Li WM, Wilson DM III, Lee CH. (2014) Altered endoribonuclease activity of APE1 variants identified in the human population.  PLoS ONE 9:e90837.

2011:

Kim W-C, Berquist BR, Chohan M, Uy C, Wilson DM III, Lee CH. (2011) Characterization of the endoribonuclease active site of human apurinic/apyrimidinic endonuclease 1 (APE1). J Mol Biol 411 :960-971.

2010:

Kim S-E, Gorrell A, Rader S, Lee CH. (2010) Endoribonuclease activity of human APE1 revealed by a real-time fluorometric assay. Anal Biochem 398: 69-75.

Tell G, Wilson DM III, Lee CH. (2010) Intrusion of a DNA-repair protein in the RNome world: is this a beginning of a new era?  Mol Cell Biol 30: 366-371.

Li W-M, Barnes T, Lee CH. (2010) Endoribonucleases: enzymes gaining spotlight in mRNA metabolism.  FEBS J 277: 627-641.

Kim W-C, King D, Lee CH. (2010) RNA-cleaving properties of human apurinic/apyrimidinic endonuclease1 (APE1). Int J Biochem Mol Biol 1: 12-25.

Lee CH. (2010) Reversing agents for ATP-binding cassette drug transporters. Methods Mol Biol 596: 325-340.

2009:

Barnes T, Kim W-C, Mantha A, Kim S-E, Izumi T, Sankar M, Lee CH.  (2009) Identification of apurinic/apyrimidinic endonuclease APE1 as the endoribonuclease that cleaves c-myc mRNA.  Nucleic Acids Res. 37: 3946-3958.

Kim W-C, Lee CH. (2009) The role of mammalian ribonucleases (RNases) in cancer.  Biochim Biophys Acta-Reviews on Cancer 1796: 99-113.

2008:

Bassett T, Harpur B, Kuo HK, Lee CH. (2008) Effective stimulation of growth in MCF-7 human breast cancer cells by inhibition of syntaxin18 by external guide sequence and ribonuclease P.  Cancer Letts 272:167-175.

2007:

Tafech A, Bennett W, Mills F, Lee CH. (2007) Identification of c-myc coding region determinant RNA sequences and structures cleaved by an RNase1-like endoribonuclease.  Biochim Biophys Acta 1769: 49-60.

Sparanese D, Lee CH.  (2007) CRD-BP shields c-myc and MDR-1 RNA from endonucleolytic attack by a mammalian endoribonuclease.  Nucleic Acids Res 35: 1209-1221.