Raine, Dr. Jason
MSc, PhD (University of Guelph)
Biography
Dr. Raine is an Adjunct Professor in Environmental Science and Operations Manager of the Quesnel River Research Centre in Likely, B.C.
Research and Expertise
Dr. Raine's research focuses on the physiological responses of fish to environmental contamination.
Selected Publications
Jamshed, L., Debnath, A., Jamshed, S., Wish, J.V., Raine, J.C., Tomy, G.T., Thomas, P.J., Holloway, A.C. 2022. An Emerging Cross-Species Marker for Organismal Health: Tryptophan-Kynurenine Pathway. International Journal of Molecular Sciences 23:6300. https://doi.org/10.3390/ijms23116300.
Su, S., Jones, P.D., Raine, J.C., Yang, Z.L., Gong, Y.F., Xie, Y.W., Tang, J., Wang, Zhao, C.X.L., Giesy, J.P. 2022. Absorption and elimination of PFAS substitutes in salmonid species after pre-fertilization exposure. Science of the Total Environment. 814:152547.
Raine, J.C., Shu, S., Lin, Y., Yang, Z.L., Giesy, J.P., Jones, P.D. 2021. Pre-fertilization exposure of rainbow trout eggs to PFAS to simulate accumulation during oogenesis. Environmental Toxicology and Chemistry 40(11): 3159-3165. DOI: 10.1002/etc.5200.
Wish, J., Bulloch, P., Oswald, L., Halldorsona, T., Raine, J.C., Jamshed L., Marvin, C., Thomas, P.J., Holloway, A.C., Tomy, G.T. 2021. Kynurenine to tryptophan ratio as a biomarker of acute stress in fish. Chemosphere 288: 132522. DOI: https://doi.org/10.1016/j.chemosphere.2021.132522.
Chao, W., Deng, F., Tang, J., Codling G., Challis J.K., Green, D., Wang. J., Chen, Q., Xie, Y., Shu S., Yang, Z., Raine, J.C., Jones, P.D., Tang, S., Giesy, J.P. 2021. Remodeling of Arctic char (Salvelinus alpinus) lipidome under a stimulated scenario of Arctic warming. Global Change Biology 27:3282–3298. DOI: https://doi.org/10.1111/gcb.15638.
Parrott, J.L., Raine, J.C., McMaster, M.E., Hewitt, L.M. 2019. Chronic toxicity of oil sands tailings pond sediments to early life stages of fathead minnow (Pimephales promelas). Heliyon 5:e02509. DOI: https://doi.org/10.1016/j.heliyon.2019.e02509.
Nazeri, S., Amiri, M, Farahmand, H., Raine, J.C. 2019. Triiodothyronine reduces toxic effects of diazinon in Persian sturgeon (Acipenser persicus) embryos. Comp. Biochem. Physiol. Part C: Toxicol. Pharmacol. 224: e108557. DOI: https://doi.org/10.1016/j.cbpc.2019.06.001.
Raine, J.C., Turcotte, D., Romanowski, L., Parrott, J.L. 2018. Oil sands tailings pond sediment toxicity to early life stages of northern pike (Esox lucius). Science of the Total Environment. 624: 567-575. DOI: https://doi.org/10.1016/j.scitotenv.2017.12.163.
Raine, J.C., Turcotte, D., Tumber, V., Peru K.M., Wang, Z., Yang, C., Headley, J.V., Parrott, J.L. 2017. Development of a bioassay to assess the toxicity of oil sands sediments to embryo-larval walleye (Sander vitreus). Environmental Pollution. 229: 798-809. DOI: https://doi.org/10.1016/j.envpol.2017.06.038.
Raine, J.C., Peitrock, M., Wilner, K., Chung, K., Turcotte, D., Parrott, J.L. 2017. Parasitological analysis and gill histopathology of pearl dace (Semotilus margarita) and brook stickleback (Culaea inconstans) collected from the Athabasca oil sands area (Canada). Bull. Env. Contam. Toxicol. 98: 733-739. DOI: https://doi.org/10.1007/s00128-017-2078-6.
Raine, J.C., Lallemand, L., Janz, D.M. 2016. Effect of chronic dietary selenomethionine exposure on the visual system of adult and F1 generation zebrafish (Danio rerio). Bull. Env. Contam. Toxicol. 97: 331-336. DOI: https://doi.org/10.1007/s00128-016-1849-9.
Driessnack, M.K., Matthews, A.L., Raine, J.C., Niyogi, S. 2016. Interactive effects of chronic waterborne copper and cadmium exposure on tissue-specific metal accumulation and reproduction in fathead minnow (Pimephales promelas). Comp. Biochem. Physiol. C. Pharmacol. Toxicol. 179: 165-173. DOI: https://doi.org/10.1016/j.cbpc.2015.10.009.
Eisner B.K., Doering, J.A., Beitel, S.C., Wiseman, S., Raine, J.C., Hecker, M. 2015. Cross-species comparison of relative potencies and relative sensitivities of fishes to dibenzo-p-dioxins, dibenzofurans, and polychlorinated biphenyls in vitro. Environ. Toxicol. Chem. 35: 173-181. DOI: https://doi.org/10.1002/etc.3173.
Su, G., Zhang, X., Raine, J.C., Xing, L, Liu, H., Higley, E., Hecker, M., Giesy, J.P., Yu, H. 2013. Mechanisms of toxicity of triphenyltin chloride (TPTC) determined by a live cell reporter array. Environ.Sci. Pollution Res. 20: 803-811. DOI: https://doi.org/10.1007/s11356-012-1280-7.
Coffin, A.B., Raine, J.C., Hawryshyn, C.W. 2012. Exposure to thyroid hormone in ovo affects otolith crystallization in rainbow trout Oncorhynchus mykiss. Environ. Biol. Fishes. 95: 347-354. DOI: https://doi.org/10.1007/s10641-012-0007-4.
Wiseman, S., Tomas, J.K., McPhee, L., Hursky, O., Raine, J.C., Pietrock, M., Giesy, J.P., Hecker, M. and Janz, D.M. 2011a. Attenuation of the cortisol response to stress in female rainbow trout chronically exposed to dietary selenomethionine. Aquat. Toxicol. 105: 643-651. DOI: https://doi.org/10.1016/j.aquatox.2011.09.002.
Wiseman, S., Tomas, J.K., Higley, E., Hursky, O., Pietrock, M., Raine, J.C., Giesy, J.P., Janz, D.M. and Hecker, M. 2011b. Chronic exposure to dietary selenomethionine increases gonadal steroidogenesis in female rainbow trout. Aquat. Toxicol. 105: 218-226. DOI: https://doi.org/10.1016/j.aquatox.2011.06.012.
Raine, J.C., Coffin, A.B. and Hawryshyn, C.W. 2011. In ovo thyroxine exposure alters later retinal remodeling in rainbow trout. J. Exper. Biol. 214: 2248-2257. DOI: https://doi.org/10.1242/jeb.055566.
Caruso, M.A., Blaufussa, P.C, Kittilson, J.D, Raine, J.C., Sheridan, M.A. 2010. Rainbow trout (Oncorhynchus mykiss) possess a fourth insulin receptor-encoding mRNA that is differentially expressed. Gen. Comp. Endocrinol. 169: 258-268. DOI: https://doi.org/10.1016/j.ygcen.2007.09.006.
Raine, J.C., Coffin, A.B. and Hawryshyn, C.W. 2010. Systemic thyroid hormone is necessary and sufficient to induce ultraviolet-sensitive cone loss in the juvenile rainbow trout retina. Journal of Experimental Biology. 213: 493-501. DOI: https://doi.org/10.1242/jeb.036301.
Raine, J.C. and Hawryshyn, C.W. 2009. Changes in thyroid hormone reception precede SWS1 opsin down-regulation in trout retina. J. Exp. Biol. 212: 2781-2788. DOI: https://doi.org/10.1242/jeb.030866.
Malkuch, H., Walock, C., Kittilson, J.D., Raine, J.C. and Sheridan M.A. 2008. Differential expression of preprosomatostatin- and somatostatin receptor-encoding mRNAs in association with the growth hormone-insulin-like growth factor system during embryonic development of rainbow trout (Oncorhynchus mykiss). Gen. Comp. Endocrinol. 159: 136-142. DOI: https://doi.org/10.1016/j.ygcen.2008.08.005.
Caruso, M., Kittilson, J., Raine, J.C. and Sheridan, M.A. 2008. Rainbow trout (Oncorhynchus mykiss) possess two insulin-encoding mRNAs that are differentially expressed. Gen. Comp. Endocrinol. 155: 695-704. DOI: https://doi.org/10.1016/j.ygcen.2007.09.006.
Raine, J.C. and Leatherland, J.F. 2008. Investigation of the transformation of the endostyle to thyroid tissue in sea lamprey, Petromyzon marinus, using T4-immunostaining. J. Fish Biol. 72:1544-1552. DOI: https://doi.org/10.1111/j.1095-8649.2008.01825.x.
Alderman, S., Raine, J.C. and Bernier, N.J. 2008. Distribution and regional stressor-induced regulation of corticotropin-releasing factor binding protein in rainbow trout (Oncorhynchus mykiss). J. Neuroendocrinol. 20: 347-358.
Li, M., Raine, J.C. and Leatherland, J.F. 2007. Expression profiles of growth-related genes during the very early development of rainbow trout embryos reared at two incubation temperatures. Gen. Comp. Endocrinol. 153: 302-310. DOI: https://doi.org/10.1016/j.ygcen.2007.02.012.
Raine, J.C., Hua, K., Bureau, D.P., Vijayan, M.M. and Leatherland, J.F. 2007. Influence of ration level and rearing temperature on hepatic GHR1 and 2, and hepatic and intestinal TRα and TRβ gene expression in late stages of rainbow trout embryos. J. Fish Biol. 71: 148-162. DOI: https://doi.org/10.1111/j.1095-8649.2007.01476.x.
Li, M., Greenaway, J., Raine, J.C., Petrik, J., Hahnel, A., Leatherland, J.F. 2006. Growth hormone and insulin-like growth factor gene expression prior to the development of the pituitary gland in rainbow trout (Oncorhynchus mykiss) embryos reared at two temperatures. Comp. Biochem. Physiol. A Mol. Integr. Physiol. 3: 514-522. DOI: https://doi.org/10.1016/j.cbpa.2006.01.024.
Raine, J.C., Strelive, U. and Leatherland, J.F. 2005. The thyroid tissue of juvenile rainbow trout, Oncorhynchus mykiss is tubular, not follicular. J. Fish Biol. 67: 823-833.
Raine, J.C., Cameron, C., Vijayan, M.M., MacKenzie, D.S. and Leatherland, J.F. 2005. Effect of fasting on thyroid hormone levels, and TRα and TRβ mRNA accumulation in late-stage embryo and juvenile rainbow trout, Oncorhynchus mykiss. Comp. Biochem. Physiol. A Mol. Integr. Physiol. 140: 452–459.
Raine, J.C., Cameron, C., Vijayan M.M., LaMarre, J. and Leatherland, J.F. 2004. The effect of elevated oocyte triiodothyronine content on development of rainbow trout embryos and expression of mRNA encoding for thyroid hormone receptors. J. Fish Biol. 65: 206-226.
Raine, J.C. and Leatherland J.F. 2003. Trafficking of L-triiodothyronine between ovarian fluid and oocytes of rainbow trout (Oncorhynchus mykiss). Comp. Biochem. Physiol. B Biochem. Mol. Biol. 136: 267-274.
Raine, J.C., Takemura, A. and Leatherland, J.F. 2001. Assessment of thyroid function in adult medaka (Oryzias latipes) and juvenile rainbow trout (Oncorhynchus mykiss) using immunostaining methods. J. Exp. Zool. 290: 366-378. DOI: https://doi.org/10.1002/jez.1077
Raine, J.C. and. Leatherland, J.F. 2000. Morphological and functional development of the thyroid tissue in rainbow trout (Oncorhynchus mykiss) embryos. Cell Tiss. Res. 301: 235-234.
Raine, J.C. and Leatherland, J.F. 1999. Ontogeny of thyroid tissue and tissue thyroid hormone clearance in rainbow trout embryos reared at two temperatures. Fish Physiol. Biochem. 20: 209-217.